Welcome to the BioGRID Download File Repository
Please use the file navigator below to browse and download archived BioGRID project files. All data provided are 100% freely available to both academic and commercial users under the MIT License, and are provided WITHOUT ANY WARRANTY. If you have any questions, please feel free to contact us.
Publications are requested to please cite the original contributing authors (where applicable) and also:
Stark C, Breitkreutz BJ, Reguly T, Boucher L, Breitkreutz A, Tyers M. Biogrid: A General Repository for Interaction Datasets. Nucleic Acids Res. Jan 1, 2006; 34:D535-9.
DOWNLOAD: Raw genetic interaction datasets- Pair-wise interaction format.zip
Full data set of 550,000 negative and 350,000 positive genetic interactions available as a raw dataset zip file posted here: http://thecellmap.org/costanzo2016/
Contains raw interaction data (SGA scores and p-values) for all tested pairs with one filter applied. For cases where reciprocal double mutant strains were constructed for the same pair of mutants (i.e. A-B and B-A), both pairs were filtered out if both interactions were significant and met the intermediate threshold (p-value < 0.05 and |score| > 0.08), but had opposite signs (e.g. A-B was negative and B-A was positive).
The tab-delimited file has 11 columns:
- 1.) Query Strain ID
- 2.) Query allele name
- 3.) Array Strain ID
- 4.) Array allele name
- 5.) Arraytype/Temp
- 6.) Genetic interaction score (e)
- 7.) P-value
- 8.) Query single mutant fitness (SMF)
- 9.) Array SMF
- 10.) Double mutant fitness
- 11.) Double mutant fitness standard deviation
File Size: 497.41 MB
Last Modified: October 28th, 2017 - 01:14:07 AM EST
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